Content overview: “Cornell’s New Two-Photon Imaging Tracks Cell Metabolism in Real Time for Faster Drug Scree”. Cornell University researchers have developed a faster two-photon fluorescence imaging method that can observe cell metabolism in real time, potentially accelerating the screening of new therapeutic treatments. The technique, detailed in a study published Sept. 4 in Science Advances, was co-led by former postdoctoral researcher Lu Ling, Ph.D. '20, and doctoral student Jack Crowley, M.S.
This advancement addresses a key bottleneck in drug development by enabling rapid, dynamic visualization of metabolic activity within living cells. By capturing metabolic changes as they happen, the method could help researchers quickly assess how cells respond to drug candidates, reducing the time and cost of bringing new therapies to market. The Cornell team’s innovation builds on two-photon microscopy, which uses near-infrared light to image deep into tissues with minimal damage, but improves its speed to capture fast biological processes. This listing links straight to the original page, where the content is available in full.