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Natural RNA Modifications in Archaea Mirror Those Used in Medicine, Weizmann and Regensburg Researchers Find

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Natural RNA Modifications in Archaea Mirror Those Used in Medicine, Weizmann and Regensburg Researchers Find

Here is what the page “Natural RNA Modifications in Archaea Mirror Those Used in Medicine, Weizmann and Regensbur” contains. Scientists at the Weizmann Institute of Science in Israel and the University of Regensburg in Germany have discovered that archaea naturally produce RNA modifications previously thought to be exclusive to synthetic therapeutic molecules. The study, published in the journal Cell, reveals that these single-celled organisms incorporate phosphorothioate modifications into their RNA backbone—a chemical alteration used in RNA-based drugs to enhance stability and efficacy. Led by Professor Schraga Schwartz and Dr.

Dina Grohmann, the research identifies the natural 'writer' machinery responsible for these modifications, marking the first evidence of such epitranscriptomic marks in nature. The findings suggest that the fundamental chemistry exploited by modern medicine has deep evolutionary roots, potentially opening new avenues for understanding RNA biology and improving therapeutic design. For the complete material, the listing points back to the source inside the network.

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